Sarah M. from Des Moines, Iowa
booked a strategy call
2 minutes ago
Your Labs Were "Normal." But You're Not Well.
Conventional labs are designed to rule out disease — not find dysfunction. Our advanced functional testing reveals what's actually happening at the cellular level — so we can build a protocol that actually works.
Root-Cause Consultation
Advanced Lab Testing
At-Home ConvenienceWhy Standard Labs Miss the Mark
Conventional labs are calibrated to detect disease — not dysfunction. By the time your markers are "out of range," you've often been suffering for years.
"Normal" labs don't mean healthy
Standard reference ranges are drawn from a sick population — dysfunction can hide inside "normal" for years.
"Normal" Ranges Are Too Wide
Lab reference ranges are based on the average of a sick population. Being in the bottom 2.5% of a diseased group is not the same as being healthy.
Only 7 Markers Tested
A standard metabolic panel checks 7–14 markers. A comprehensive functional workup analyzes 200+ biomarkers across every body system.
Serum ≠ Cellular Levels
Blood serum levels of nutrients like magnesium and B12 can appear normal while cells are severely depleted. We test what's actually inside your cells.
No Functional Markers
Standard labs never check organic acids, hormone metabolites, gut pathogens, or methylation — the markers that reveal how your body actually functions.
Treated as Isolated Numbers
A single lab value means nothing without context. Functional medicine interprets every marker in relation to your symptoms, history, and other results.
Designed for Diagnosis, Not Prevention
Conventional labs are designed to diagnose disease after it's already developed — not to identify the dysfunction that causes disease years before it appears.
Testing That Tells the Whole Story
Every patient receives a personalized lab panel based on their symptoms, history, and health goals. We don't run the same panel on everyone — we run the right tests for you.
Optimal Ranges, Not Just "Normal"
Conventional labs flag you as normal if you're in the bottom 2.5% of a sick population. We use functional optimal ranges that reflect true health.
Advanced Specialty Labs
We partner with Genova Diagnostics, Cyrex Labs, Great Plains Laboratory, and Doctor's Data — the gold standard in functional testing.
Interpreted in Context
A lab value means nothing in isolation. We interpret every marker in the context of your symptoms, history, and the full clinical picture.
Root-Cause Focused
We're not looking for a diagnosis to match a drug. We're looking for the underlying dysfunction driving your symptoms — then correcting it.
Root Cause Analysis
We investigate why, not just what
Genetic Insight
MTHFR, detox pathways, and more
Cellular Testing
Intracellular, not just serum
Specialty Labs
Genova, Cyrex, Great Plains
Full-Body Insight
Gut, hormones, brain, immune
Optimal Ranges
Health, not just disease-free
The Labs We Run — and Why
Each panel is selected based on your specific symptoms and goals. Here's what we test and why it matters.
Comprehensive Thyroid Panel
Standard TSH alone misses 70% of thyroid dysfunction. Our full panel reveals conversion problems, autoimmune attacks, and cellular resistance.
Tests Included
- TSH
- Free T3
- Free T4
- Reverse T3
- TPO Antibodies
- Thyroglobulin Antibodies
DUTCH Hormone Panel
The gold standard in hormone testing. Dried urine captures hormone metabolites across a full day — far more accurate than a single blood draw.
Tests Included
- Estrogen Metabolites (E1, E2, E3)
- Progesterone
- DHEA-S
- Cortisol Rhythm
- Testosterone
- Melatonin
GI-MAP Stool Analysis
DNA-based stool testing identifies pathogens, parasites, and microbiome imbalances that standard stool cultures completely miss.
Tests Included
- H. pylori
- Parasites & Worms
- Candida & Fungi
- Zonulin (Leaky Gut)
- Secretory IgA
- Beneficial Bacteria Levels
Organic Acids Test (OAT)
A single urine test that reveals metabolic dysfunction at the cellular level — showing how well your body produces energy, detoxifies, and makes brain chemicals.
Tests Included
- Mitochondrial Function Markers
- Neurotransmitter Metabolites
- Yeast & Bacterial Overgrowth
- Oxalate Levels
- Vitamin & Mineral Status
- Detoxification Capacity
Food Sensitivity Testing (IgG/IgA)
Unlike IgE allergy tests, this identifies delayed (24–72 hour) immune reactions that cause chronic inflammation, brain fog, and gut damage.
Tests Included
- 200+ Food Antigens
- IgG Delayed Reactions
- IgA Mucosal Reactions
- Lectin Sensitivity
- Gluten/Gliadin Antibodies
- Cross-Reactive Foods
Advanced Metabolic Panel
Standard cholesterol panels miss 50% of cardiovascular risk. We look at insulin resistance, inflammation, and lipoprotein particle size — the real predictors.
Tests Included
- Fasting Insulin & HOMA-IR
- HbA1c & Fasting Glucose
- NMR Lipoprofile (particle size)
- Homocysteine
- hs-CRP (inflammation)
- Uric Acid
MTHFR & Methylation Panel
40% of the population carries MTHFR mutations affecting detox, neurotransmitters, and cardiovascular health. Standard labs never check this.
Tests Included
- MTHFR C677T & A1298C
- Homocysteine
- Folate (RBC)
- B12 (Active)
- SAM/SAH Ratio
- CBS & COMT Variants
Heavy Metals & Toxin Panel
Environmental toxins accumulate silently for years, disrupting hormones, neurological function, and immune regulation. Most doctors never test for them.
Tests Included
- Mercury, Lead, Arsenic, Cadmium
- Aluminum & Nickel
- Glyphosate (Roundup)
- BPA & Phthalates
- Mycotoxins (Mold Toxins)
- Organophosphate Pesticides
Micronutrient & Mineral Panel
Serum levels of nutrients are often normal even when cells are depleted. Intracellular testing reveals the true nutritional status driving your symptoms.
Tests Included
- Intracellular Magnesium
- Zinc & Copper Ratio
- Vitamin D (25-OH)
- Vitamin B12 & Folate
- Iron Studies (Ferritin, TIBC)
- Selenium & Iodine
From Confusion to Clarity
Our lab testing process is designed to be simple, convenient, and actionable.
Strategy Call
We review your symptoms, history, and goals to determine which panels are right for you.
Lab Kit Shipped
Most tests are done at home with a urine, stool, or dried blood spot kit mailed directly to you.
Results Analyzed
We receive your results and spend hours analyzing every marker in context — not just flagging out-of-range values.
Action Plan Delivered
You receive a personalized protocol with targeted nutrition, supplements, and lifestyle changes based on your results.
Dr. Brandon Mannie
Board-Certified Functional Medicine Practitioner
Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.
Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.
Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.
"I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
Amazing Patient Transformations
Are You Next?
JACKIE
Down 47 Pounds!
- Improved Energy!
- Improved Self Confidence!
- Sleeping Better!
- Less Anxiety / Depression!
DEB
Down 32 Pounds!
- Improved Digestion!
- Increased Energy Throughout The Day!
- Loving Life Again!
BRITTNEY
Down 53 Pounds!
- Improved Energy & Less Afternoon Fatigue!
- Improved Confidence!
KELLY
Down 34 Pounds!
- Less Fatigue!
- Improved Sleep!
KAREN
Down 32 Pounds!
- Brain Fog Gone!
- Less Tired!
- Better GI Function!
JACKIE
Down 27 Pounds!
- Improved Energy!
- Greater Mental Clarity!
SUE
Down 54 Pounds!
- Less Inflammation!
- Less Fatigue!
- Improved Gut Health!
AMANDA
Down 64 Pounds!
- Improved Energy!
- Loving Life Again!
JACKIE
Down 47 Pounds!
- Improved Energy!
- Improved Self Confidence!
- Sleeping Better!
- Less Anxiety / Depression!
DEB
Down 32 Pounds!
- Improved Digestion!
- Increased Energy Throughout The Day!
- Loving Life Again!
BRITTNEY
Down 53 Pounds!
- Improved Energy & Less Afternoon Fatigue!
- Improved Confidence!
KELLY
Down 34 Pounds!
- Less Fatigue!
- Improved Sleep!
KAREN
Down 32 Pounds!
- Brain Fog Gone!
- Less Tired!
- Better GI Function!
JACKIE
Down 27 Pounds!
- Improved Energy!
- Greater Mental Clarity!
SUE
Down 54 Pounds!
- Less Inflammation!
- Less Fatigue!
- Improved Gut Health!
AMANDA
Down 64 Pounds!
- Improved Energy!
- Loving Life Again!
Frequently Asked Questions
Ready to Stop Guessing and Start Testing?
Book a 1-on-1 strategy call with Dr. Brandon Mannie's clinical team. No obligation, no hard sell — just clinical clarity on which functional labs will reveal your root cause.
