Sarah M. from Des Moines, Iowa
booked a strategy call
2 minutes ago
Backed by Actual Lab Data, Not Guesswork. Comprehensive Stool DNA. Pathogen Screen. Immune Markers. Gut Permeability. Nutrient Absorption. We measure all of it.
Gut Distress
Pathogen Labs
Gut NutritionSelect every statement that applies to you. Your severity grade updates below as you check boxes.
You were told your gut issues are 'just IBS' and handed an antispasmodic. Year after year, the symptoms persist — and nobody ever ran comprehensive DNA stool testing.

Hidden pathogens steal nutrients, damage the gut lining, and trigger systemic inflammation — driving fatigue, brain fog, skin issues, and cravings.
You're handed medications for bloating, diarrhea, and pain — but the parasites driving your symptoms are never identified or cleared.
Conventional stool tests use outdated microscopy that misses most parasites. DNA-based PCR testing is far more accurate but rarely ordered.
Parasites cause fatigue, brain fog, skin issues, and cravings — but these are treated as separate problems, never connected to the gut.
Standard panels check basic blood counts alone — skipping comprehensive DNA stool, pathogen screens, leaky gut markers, and absorption testing.
You're handed medications for each gut symptom while the parasites driving them are never identified or cleared.
Conventional stool tests use outdated microscopy that misses most parasites. DNA-based PCR testing is far more accurate but rarely ordered.
Parasite-driven gut issues are routinely dismissed as IBS or food intolerance — leaving the real cause untreated for years.
Conventional care focuses on lifelong symptom management rather than identifying and clearing the pathogens damaging your gut.

We run comprehensive DNA stool PCR, pathogen screens, leaky gut markers, absorption testing, and immune markers — not just basic labs.
A targeted plan using evidence-based antimicrobials and therapeutic nutrition to clear identified pathogens safely and effectively.
After clearance, we seal the gut lining, reduce inflammation, and reinoculate beneficial flora to restore a healthy microbiome.
Regular follow-up testing and protocol adjustments ensure pathogens are cleared and your gut health is fully restored.
DNA-based PCR testing detects parasites and pathogens that outdated microscopy misses — the core test conventional medicine rarely runs.
Parasites damage the gut lining — measuring permeability reveals the leaky gut driving your systemic symptoms.
Parasites steal nutrients and impair digestion — measuring absorption reveals why you're deficient despite eating well.
Quantifies the gut inflammation and immune activation caused by chronic pathogen burden.
Parasites deplete key nutrients — measuring status reveals deficiencies and guides precise repletion.
Pathogen damage creates food sensitivities that inflame the gut and block healing until they're identified.

Standard workups use outdated stool microscopy that misses most parasites — skipping DNA-based PCR, leaky gut markers, and absorption testing — leaving the true pathogen drivers hidden.
clearance rate with our targeted parasite protocol

Board-Certified Functional Medicine Practitioner
Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.
Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.
Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.
"I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
These are the stories of patients who were told there was nothing more that could be done — and who chose to look deeper.

"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong."
"After 4 years on Metformin and still feeling exhausted, Dr. Mannie found my issue was cellular resistance and gut inflammation. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
Book a 1-on-1 strategy call with Dr. Brandon Mannie's clinical team. No obligation, no hard sell — just clinical clarity on your path to gut restoration.