Sarah M. from Des Moines, Iowa
booked a strategy call
2 minutes ago
Backed by Actual Lab Data, Not Guesswork. Heavy Metals. Mycotoxins. Environmental Chemicals. Detox Genetics. Organic Acids. We measure all of it.
Toxic Burden
Advanced Toxin Labs
Cellular RepairSelect every statement that applies to you. Your severity grade updates below as you check boxes.
You're exposed to thousands of environmental toxins every day. When your detox pathways become overwhelmed, chronic illness follows — and no one is testing for the actual burden.

The average American carries hundreds of synthetic chemicals in their blood and urine — and standard medicine never tests for a single one.
Your liver, kidneys, lymph, and skin were never built to handle the modern toxic load. When the burden exceeds capacity, toxins store in your cells, tissues, and fat — triggering inflammation and chronic disease.
Juice cleanses and fad detoxes stir up toxins without safely binding and eliminating them — causing them to recirculate and often making you feel worse, not better.
Mycotoxins from water-damaged buildings accumulate in nervous and immune tissue, driving brain fog, fatigue, and mood disorders that no standard workup ever finds.
Mercury, lead, and arsenic impair cellular energy production and disrupt endocrine signaling — yet conventional medicine almost never tests for them.
Conventional doctors never run heavy metal, mycotoxin, or environmental chemical panels — so the true toxic burden stays completely invisible while symptoms worsen.
Brain fog, fatigue, and hormone issues get labeled and medicated — while the underlying toxin accumulation driving them is never identified or addressed.
MTHFR, COMT, and GST variants determine how well you clear toxins. Standard care never checks these — so genetically impaired detoxers stay sick indefinitely.
Mobilizing toxins without opening liver, bile, kidney, and lymph drainage causes recirculation and healing crises. Conventional protocols skip this critical step entirely.

We run heavy metals, mycotoxins, environmental chemicals, organic acids, and detox genetics (MTHFR, COMT) — you can't treat what you haven't identified.
Before mobilizing anything, we ensure your liver, bile ducts, kidneys, lymphatics, and colon are open — preventing toxins from recirculating and worsening symptoms.
Using targeted binders — activated charcoal, zeolite, chlorella, and DMSA for metals — we safely pull toxins from tissues and bind them for elimination before reabsorption.
Once the burden is cleared, we restore mitochondrial function, reduce inflammation, rebalance hormones, and build a lifestyle protocol to prevent future accumulation.
Heavy metals disrupt cellular energy production, hormones, and neurological function. We test blood and urine to quantify your true metal burden.
Mold mycotoxins from water-damaged buildings accumulate in the nervous system and immune tissue — a root driver of chronic fatigue and brain fog.
Endocrine-disrupting plastics, herbicides, and solvents burden your liver detox pathways and silently drive hormonal and metabolic dysfunction.
Your genetic detox capacity determines how efficiently you clear toxins. Impaired methylation means toxins recirculate instead of being eliminated.
Organic acids reveal mitochondrial dysfunction and nutrient deficiencies that limit your cells' ability to run the detox machinery.
Before mobilizing toxins, drainage pathways must be open. Sluggish bile and leaky gut cause mobilized toxins to recirculate and worsen symptoms.

Standard care never runs heavy metal, mycotoxin, or environmental toxin testing — leaving the true toxic burden hidden while symptoms worsen year after year.
synthetic chemicals detected in the average American's blood & urine (CDC)

Board-Certified Functional Medicine Practitioner
Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.
Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.
Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.
"I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
These are the stories of patients who were told there was nothing more that could be done — and who chose to look deeper.

"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong."
"After 4 years on Metformin and still feeling exhausted, Dr. Mannie found my issue was cellular resistance and gut inflammation. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
Book a 1-on-1 strategy call with Dr. Brandon Mannie's clinical team. No obligation, no hard sell — just clinical clarity on your path to cellular detoxification.