Sarah M. from Des Moines, Iowa
booked a strategy call
2 minutes ago
Backed by Actual Lab Data, Not Guesswork. Neurotransmitters. Hormones. Inflammation. Mitochondria. Toxins. Food Sensitivities. We measure all of it.
Neuro-Inflammation
Neuro Labs
Trigger-Free NutritionSelect every statement that applies to you. Your severity grade updates below as you check boxes.
You were handed a prescription and told to 'avoid stress.' Attack after attack, the meds increase and the migraines keep coming — and nobody ever asks why your nervous system is inflamed.

Untreated neuro-inflammation progressively lowers your attack threshold — turning occasional migraines into chronic daily pain.
Triptans and painkillers abort the attack but never address why your neurons are hyper-excitable and inflamed in the first place.
Low serotonin, dopamine, and GABA directly lower your migraine threshold. Standard care never measures these.
Your brain's energy factories underperform, making neurons fire erratically. CoQ10, magnesium, and B-vitamin status are rarely tested.
Standard workups check basic labs alone — skipping hormones, toxins, food sensitivities, and inflammatory markers that drive your attacks.
You're handed abortive and preventive drugs. Year after year the dose increases and nobody asks why your neurons are inflamed.
Standard workups check basic blood counts, skipping neurotransmitters, hormones, mitochondrial markers, toxins, and food zoomers.
Food sensitivities, hormonal patterns, and environmental toxins are dismissed as 'unavoidable' rather than tested and removed.
Conventional care focuses on lifelong drug management rather than restoring neurological balance so you can reduce or eliminate medication.

We run neurotransmitter panels, hormones, inflammatory markers, mitochondrial nutrients, toxins, and food sensitivity zoomers — not just basic labs.
A therapeutic nutrition plan built around your specific food sensitivities, hormonal patterns, and environmental exposures.
Evidence-based nutraceuticals like magnesium, CoQ10, riboflavin, and B6 — dosed precisely from your labs — plus gut lining repair.
Regular follow-up labs and protocol adjustments ensure you're progressing toward fewer attacks, with a plan for safely reducing medications.
Low inhibitory neurotransmitters and high excitatory ones directly lower your migraine threshold.
Hormonal fluctuations — especially estrogen drops — are one of the most common, and most missed, migraine triggers.
Systemic inflammation sensitizes neurons and lowers the threshold for an attack.
Mitochondrial energy deficits make brain cells fire erratically — these nutrients are essential for prevention.
Hidden food sensitivities and biogenic amines silently trigger attacks that are never connected to your diet.
Neurotoxins accumulate in brain tissue and chronically hyper-excite neurons, driving recurring attacks.

Standard workups check basic blood counts alone — skipping neurotransmitters, hormones, mitochondrial markers, toxins, and food sensitivities — leaving the true migraine drivers hidden.
reduction in migraine frequency with root-cause functional intervention

Board-Certified Functional Medicine Practitioner
Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.
Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.
Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.
"I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
These are the stories of patients who were told there was nothing more that could be done — and who chose to look deeper.

"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong."
"After 4 years on Metformin and still feeling exhausted, Dr. Mannie found my issue was cellular resistance and gut inflammation. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
Book a 1-on-1 strategy call with Dr. Brandon Mannie's clinical team. No obligation, no hard sell — just clinical clarity on your path to a migraine-free life.