Sarah M. from Des Moines, Iowa
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You Were Told to Manage It Forever. We Disagree. Discover the Real Drivers of Your Blood Sugar Dysfunction
Backed by Actual Lab Data, Not Guesswork. Fasting Insulin. HOMA-IR. GI-Map. Cortisol. Hormones. Toxins. Nutrients. We measure all of it.
Daily Monitoring
Advanced Labs
Therapeutic NutritionFind Out If You Qualify For Our Functional Diabetes Protocol
Do You Experience Any Of These Diabetes Symptoms?
Select every statement that applies to you. Your severity grade updates below as you check boxes.
Why Conventional Medicine Is Failing Diabetics
You were handed a prescription, told to "watch your carbs," and sent home. Year after year, your dose increases and your A1C creeps up — and nobody ever asks why your blood sugar is dysregulated.
1 in 3 will develop vision loss
Untreated insulin resistance quietly damages every system in your body — heart, brain, kidneys, nerves, and eyes.
Managing Blood Sugar, Not Fixing Insulin Resistance
Medications lower the number on the meter but never address why your cells stopped responding to insulin in the first place. The resistance worsens silently while your dose keeps climbing.
Metformin Depletes Critical Nutrients
Long-term metformin use depletes B12, magnesium, and other nutrients essential for nerve and metabolic health — accelerating neuropathy and fatigue that the drugs were meant to prevent.
Gut Dysbiosis Drives Blood Sugar
A disrupted microbiome directly impairs glucose metabolism and increases leaky gut inflammation. Standard care never runs a GI-Map, so the real driver stays hidden.
The System Misses the Real Drivers
Standard panels check A1C and fasting glucose alone — skipping fasting insulin, HOMA-IR, cortisol, hormones, toxins, and gut mapping that reveal why your blood sugar is out of control.
The System Is Not Built to Reverse Diabetes
Symptom Management, Not Root Cause Resolution
You're handed a prescription and told to 'watch your carbs.' Year after year the dose increases, the A1C creeps up, and nobody asks why your blood sugar is dysregulated.
Incomplete Diagnostic Workups
Standard workups check A1C and fasting glucose, skipping fasting insulin, HOMA-IR, gut mapping, cortisol, hormones, and toxin screens that reveal the true metabolic drivers.
Prediabetes Is Dismissed Until It's Too Late
Prediabetes is brushed off as 'borderline' until it becomes full diabetes — missing the critical window where insulin resistance is fully reversible.
No Pathway to Medication Reduction
Conventional care focuses on lifelong drug management rather than restoring insulin sensitivity, gut health, and metabolic function so you can reduce or eliminate medication.
A Natural Functional Approach to Diabetes Reversal
Advanced Metabolic Testing
We run full insulin panels, HOMA-IR, organic acids, comprehensive thyroid, cortisol, heavy metals, GI-Map, and nutrient status — not just A1C.
Personalized Nutrition Protocol
A therapeutic nutrition plan built around your specific metabolic drivers, food sensitivities, and gut microbiome — not a generic 'diabetic diet.'
Targeted Supplementation & Gut Repair
Evidence-based nutraceuticals like berberine, magnesium, chromium, and alpha-lipoic acid — dosed precisely from your labs — plus gut lining repair.
Ongoing Monitoring & Medication Reduction
Regular follow-up labs and protocol adjustments ensure you're progressing toward remission, with a clear plan for safely reducing medications with your prescriber.
We Look Where Others Don't
Measures true insulin resistance — not just blood sugar — to catch metabolic dysfunction years before A1C ever rises.
Gut dysbiosis directly impairs glucose metabolism and drives leaky gut inflammation that worsens insulin resistance.
Cortisol, thyroid, and leptin imbalances silently keep blood sugar elevated — often missed on standard labs entirely.
Inflammatory cytokines block insulin receptor signaling, keeping glucose high even when your diet is clean.
Endocrine-disrupting toxins impair pancreatic beta cell function and insulin signaling at the cellular level.
Metformin depletes B12 and key minerals essential for glucose metabolism — we test and replete precisely.
Standard care checks A1C and fasting glucose alone — skipping fasting insulin, HOMA-IR, gut mapping, cortisol, and toxins — leaving the true metabolic drivers hidden for years.
of patients achieve remission with intensive metabolic intervention (DiRECT Trial, Lancet)
Four Pillars of Our Diabetes Protocol
Therapeutic Nutrition
- Blood sugar-stabilizing nutrition plan
- Elimination of reactive & inflammatory foods
- Gut lining repair & microbiome support
- Personalized macro & timing strategy
Targeted Supplementation
- Berberine & alpha-lipoic acid for insulin sensitivity
- Magnesium, chromium & zinc repletion
- Vitamin D3/K2 & B-vitamin support
- Glutathione & NAC for oxidative stress
Hormone & Adrenal Care
- Cortisol rhythm & HPA axis optimization
- Thyroid & sex hormone balancing
- Leptin & appetite signaling reset
- Sleep & circadian restoration
Detox & Gut Restoration
- Heavy metal & toxin binding protocols
- GI-Map guided microbiome repair
- Leaky gut (zonulin) sealing protocol
- Reinoculation of beneficial flora
Clinical Improvement Rates
Dr. Brandon Mannie
Board-Certified Functional Medicine Practitioner
Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.
Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.
Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.
"I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
Real People. Real Results.
These are the stories of patients who were told there was nothing more that could be done — and who chose to look deeper.
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong."
"After 4 years on Metformin and still feeling exhausted, Dr. Mannie found my issue was cellular resistance and gut inflammation. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
Frequently Asked Questions
Ready to Stop Managing and Start Reversing Your Diabetes?
Book a complimentary 1-on-1 strategy call with Dr. Brandon Mannie's clinical team. No obligation, no hard sell — just clinical clarity on your path to metabolic reversal.
