Sarah M. from Des Moines, Iowa
booked a strategy call
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Backed by Actual Lab Data, Not Guesswork. Full Antibody Panels. Leaky Gut (Zonulin). Mycotoxins. Stealth Infections. Food Zoomers. We measure all of it.
Autoimmune Symptoms
Antibody & Zonulin Labs
AIP Anti-Inflammatory NutritionSelect every statement that applies to you. Your severity grade updates below as you check boxes.
Over 50 million Americans suffer from autoimmune conditions — yet conventional care relies almost exclusively on immune-suppressing drugs. Here is why the standard approach fails to deliver true recovery.

Hormonal shifts, gut permeability, and chronic stress create a perfect storm for immune dysregulation.
Conventional treatments rely on steroids and immunosuppressants to turn off symptoms. While this provides temporary relief, it leaves the underlying triggers untouched and increases infection risks.
A compromised intestinal lining allows undigested food proteins, toxins, and bacterial fragments into the bloodstream. The immune system creates antibodies against these, which mistakenly attack your own organs.
Reactivated Epstein-Barr (EBV), Lyme, mold mycotoxins, and heavy metal toxicity continuously hyper-stimulate immune receptors, keeping your body stuck in a perpetual flare state.
Standard blood tests check basic inflammation (ANA/ESR) but rarely evaluate leaky gut markers (zonulin), mycotoxins, stealth viral loads, or deep food cross-reactivity.
Steroids and biologic drugs suppress your entire immune system without investigating why antibodies formed in the first place.
Standard workups check basic ANA or inflammatory markers, skipping zonulin, stealth viral loads, mycotoxins, and food zoomers.
Conventional labs only flag abnormalities when tissue damage is severe enough to alter basic blood counts — missing years of early immune activity.
Conventional care focuses on lifelong drug management rather than gut repair, toxin clearance, and restoring natural immune tolerance.

We run advanced functional immune panels — full antibody mapping, zonulin leaky gut testing, mycotoxins, stealth infections, and food zoomers — to identify your precise triggers.
We build a personalized plan incorporating anti-inflammatory therapeutic nutrition, evidence-based botanical immunomodulators, and barrier repair nutrients.
We seal the intestinal barrier, clear stealth pathogens and mycotoxins, and balance the microbiome to remove the fuel powering immune overactivation.
We track antibody levels, systemic inflammatory markers, and symptom flare frequency with regular reviews to ensure long-term immune stability.
Identifies whether your immune system is actively producing self-attacking antibodies before irreversible tissue destruction occurs.
Leaky gut allows bacterial toxins and undigested proteins into circulation, driving systemic molecular mimicry and autoimmune attacks.
Occult or stealth viral and bacterial infections continuously hyper-stimulate immune receptors, keeping the body in a permanent flare state.
Toxic burden accumulates in tissues and misfolds human proteins, tricking immune cells into treating your own organs as foreign invaders.
Quantifies systemic inflammation to evaluate treatment progress and track tissue recovery at the cellular level.
Pinpoints subtle food sensitivities that trigger immune complex formation and silent joint/tissue inflammation every time you eat.

Standard workups check basic ANA or inflammatory markers alone, skipping zonulin, stealth viral loads, mycotoxins, and food zoomers — leaving the true autoimmune triggers hidden.
Root trigger detection rate in patients previously told labs were "normal"

Board-Certified Functional Medicine Practitioner
Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.
Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.
Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.
"I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
These are the stories of patients who were told there was nothing more that could be done — and who chose to look deeper.

"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong."
"After 4 years on Metformin and still feeling exhausted, Dr. Mannie found my issue was cellular resistance and gut inflammation. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
Book a complimentary 1-on-1 strategy call with Dr. Brandon Mannie's clinical team. No obligation, no hard sell — just clinical clarity on your path forward.