Sarah M. from Des Moines, Iowa
booked a strategy call
2 minutes ago
For Those Wanting to Lose Weight in a Manner That Is SAFE, NATURAL, & Highly Effective...WITHOUT Long-Term Dependence On "Big Pharma"! 👎
FAT Melts Off The Body As A SIDE EFFECT Of Becoming Healthy...Let THAT Be Our Focus?
Find Out If You Qualify For Our Functional Protocol
Do You Experience Any Of These Symptoms?
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Amazing Patient Transformations
Are You Next?
JACKIE
Down 47 Pounds!
- Improved Energy!
- Improved Self Confidence!
- Sleeping Better!
- Less Anxiety / Depression!
DEB
Down 32 Pounds!
- Improved Digestion!
- Increased Energy Throughout The Day!
- Loving Life Again!
BRITTNEY
Down 53 Pounds!
- Improved Energy & Less Afternoon Fatigue!
- Improved Confidence!
KELLY
Down 34 Pounds!
- Less Fatigue!
- Improved Sleep!
KAREN
Down 32 Pounds!
- Brain Fog Gone!
- Less Tired!
- Better GI Function!
JACKIE
Down 27 Pounds!
- Improved Energy!
- Greater Mental Clarity!
SUE
Down 54 Pounds!
- Less Inflammation!
- Less Fatigue!
- Improved Gut Health!
AMANDA
Down 64 Pounds!
- Improved Energy!
- Loving Life Again!
JACKIE
Down 47 Pounds!
- Improved Energy!
- Improved Self Confidence!
- Sleeping Better!
- Less Anxiety / Depression!
DEB
Down 32 Pounds!
- Improved Digestion!
- Increased Energy Throughout The Day!
- Loving Life Again!
BRITTNEY
Down 53 Pounds!
- Improved Energy & Less Afternoon Fatigue!
- Improved Confidence!
KELLY
Down 34 Pounds!
- Less Fatigue!
- Improved Sleep!
KAREN
Down 32 Pounds!
- Brain Fog Gone!
- Less Tired!
- Better GI Function!
JACKIE
Down 27 Pounds!
- Improved Energy!
- Greater Mental Clarity!
SUE
Down 54 Pounds!
- Less Inflammation!
- Less Fatigue!
- Improved Gut Health!
AMANDA
Down 64 Pounds!
- Improved Energy!
- Loving Life Again!
Why Can't You Lose The Weight?
Over 70% of Americans are overweight — yet conventional medicine still blames "lack of willpower" or pushes lifelong GLP-1 injections. Here is why the standard approach fails.
The control center of your metabolism
When insulin resistance develops, every system from your brain to your toes suffers from energy starvation.
The "Eat Less, Move More" Myth
Calorie restriction alone destroys your metabolism. When your cells are resistant to insulin, they can't burn fat for fuel. Starving yourself causes muscle loss and slows metabolic rate.
It Steals Your Vitality
Weight loss resistance brings crushing fatigue, brain fog, hormonal imbalances, and joint pain — leaving you drained of daily energy.
The GLP-1 Trap (Ozempic/Wegovy)
Drugs force temporary weight loss by paralyzing digestion. When stopped, metabolism is slower, causing rapid rebound weight gain.
The Root Causes Are Being Missed
Hidden thyroid dysfunction, cellular inflammation, gut dysbiosis, cortisol dysregulation, and toxins block fat burning.
The System Is Not Built to Heal Your Metabolism
Forced Starvation, Not Root Cause Resolution
GLP-1 injections and extreme diets force temporary weight loss by starving your body, leaving cellular damage untouched.
Incomplete Diagnostic Workups
Standard workups only check A1C and glucose, ignoring fasting insulin, cellular inflammation, and gut permeability.
Ignoring Cellular Health
Conventional care forces blood sugar into cells with more insulin without repairing damaged cellular hormone receptors.
No Pathway to Metabolic Flexibility
They rarely restore your body's natural capacity to oxidize fat for fuel through targeted functional nutrition.
A Natural Functional Approach to Metabolic Healing
Comprehensive Root Cause Investigation
We run a deep-dive functional lab panel to map metabolic, hormonal, inflammatory, and toxic drivers before recommending interventions.
Personalized Metabolic Protocol
We build a customized protocol combining therapeutic nutrition, evidence-based nutraceuticals, and lifestyle medicine.
Inflammation & Metabolic Restoration
We repair gut barrier integrity (leaky gut) and reduce systemic cellular inflammation to unlock natural fat burning.
Ongoing Monitoring & Optimization
We track progress with repeat labs and strategy reviews, adapting your protocol as your cellular metabolism heals.
We Look Where Others Don't
Insulin resistance is a major driver of metabolic syndrome and cellular energy failure.
Deficiencies in these specific micronutrients directly impair insulin receptor sensitivity and metabolic function.
Chronic low-grade inflammation accelerates autoimmune destruction and blocks cellular hormone receptors.
Hidden food sensitivities trigger chronic immune reactions that inflame the gut, disrupt metabolism, and silently block weight loss.
Hormonal imbalances — thyroid, cortisol, and sex hormones — directly regulate fat storage, energy, and metabolic rate. We measure them all.
Stored toxins overwhelm your detox pathways, damage mitochondria, and force the body to sequester them in fat tissue — making weight loss nearly impossible until cleared.
A structured review identified that first-line weight loss clinics consistently omit testing for cellular inflammation, hidden thyroid dysfunction, and gut permeability.
Root cause detection rate in patients previously told labs were "normal"
Four Pillars of Metabolic Restoration
Therapeutic Nutrition
- Anti-inflammatory dietary protocol
- Blood sugar stabilization
- Gut microbiome restoration
- Elimination of neurotoxic foods
Targeted Supplementation
- Targeted compounds for insulin sensitivity
- Mitochondrial support for fat oxidation
- Nutraceuticals to balance hormones
- Magnesium Glycinate for metabolic speed
Lifestyle Medicine
- Structured movement & balance training
- Sleep optimization protocols
- Stress & cortisol management
- Infrared therapy for circulation
Detoxification Support
- Heavy metal chelation (where indicated)
- Liver & methylation support
- Sauna & lymphatic drainage
- Binders for mycotoxin clearance
Expected Clinical Progress
Dr. Brandon Mannie
Board-Certified Functional Medicine Practitioner
Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.
Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.
Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.
"I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
Real People. Real Results.
These are the stories of patients who were told there was nothing more that could be done — and who chose to look deeper.
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong."
"After 4 years on Metformin and still feeling exhausted, Dr. Mannie found my issue was cellular resistance and gut inflammation. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
"I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."
"I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."
"As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."
"The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."
"I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."
"Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."
"I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."
Everything You've Been Afraid to Ask
Ready to Finally Lose the Weight
— and Keep It Off?
Book a Strategy Call with Dr. Mannie's clinical team. We will review your health history and determine whether our functional protocol is right for you.
