Sarah M. from Des Moines, Iowa

    booked a strategy call

    2 minutes ago

    Board-Certified Practitioners|Telehealth Available Nationwide
    Book Your Strategy Call
    Strategy Call

    For Those Told Their Gut Issues Are "Just IBS" While Still Bloated, Foggy, and Exhausted — Discover WHY Your Gut Broke Down in the First Place...

    Backed by Actual Lab Data, Not Guesswork. GI-Map. Leaky Gut Markers. SIBO Breath. Food Sensitivities. We measure all of it.

    The hidden root causes of gut dysfunction conventional doctors miss.
    Why antacids & antibiotics often make things worse.
    A proven functional approach to restoring your microbiome.
    Book My Strategy Call
    Gut dysfunction and digestive distress
    Digestive Distress
    Gut-healing whole foods: leafy greens, fermented vegetables, bone broth
    Gut-Healing Nutrition
    Brain fog and the gut-brain connection
    Gut-Brain Fog
    Interactive Assessment

    Find Out If You Qualify For Our Functional Gut Protocol

    Do You Experience Any Of These Gut Symptoms?

    Select every statement that applies to you. Your severity grade updates below as you check boxes.

    0 of 12 Symptoms Selected
    Functional Gut Evaluation

    Select all symptoms that apply to evaluate your gut dysfunction risk.

    Gut Status: Unassessed
    Your Symptoms Point To Reversible Gut Drivers

    Complete this assessment to unlock a complimentary 1-on-1 Strategy Call with Dr. Brandon Mannie's clinical team.

    70M+
    Americans with digestive disease
    70%
    of your immune system lives in your gut
    95%
    of serotonin is produced in the gut
    500+
    Patients helped with our protocol
    The Core Problem

    Why Your Gut Isn't Healing

    Over 70 million Americans suffer from digestive disease — yet conventional care relies on symptom labels and acid blockers. Here is why the standard approach fails.

    Gut dysfunction and digestive distress
    Research Insight

    70% of your immune system lives in your gut

    When the microbiome breaks down, inflammation floods every system — from your brain to your joints to your skin.

    The "It's Just IBS" Dismissal

    Conventional doctors label bloating and irregularity as IBS — a symptom bucket, not a diagnosis. It tells you nothing about the dysbiosis, leaky gut, or SIBO actually driving your suffering.

    It Steals Your Energy & Clarity

    A damaged gut can't absorb nutrients. The result is crushing fatigue, brain fog, and mood swings — because 95% of your serotonin and most of your immune system live in your gut.

    The Antacid & Antibiotic Trap

    Acid blockers and repeated antibiotics wipe out your microbiome, starve you of stomach acid, and feed pathogenic overgrowth — making the root cause worse with every prescription.

    The Root Causes Are Being Missed

    Hidden dysbiosis, intestinal permeability, SIBO, parasites, and Candida overgrowth are almost never tested — yet they drive the inflammation behind dozens of chronic conditions.

    Why Conventional Medicine Falls Short

    The System Is Not Built to Heal Your Gut

    01

    Symptom Suppression, Not Root Cause Resolution

    Antacids, antispasmodics, and antibiotics mask bloating and reflux while leaving dysbiosis, leaky gut, and microbial overgrowth completely untouched.

    02

    Incomplete Diagnostic Workups

    Standard workups check basic bloodwork alone, omitting DNA stool analysis (GI-Map), leaky gut markers, breath testing, and food sensitivity panels.

    03

    Outdated Testing Misses the Breakdown

    Conventional stool cultures miss 90% of the microbiome. Patients sit inside 'normal' results for years while pathogens and inflammation destroy the gut lining.

    04

    No Pathway to Microbiome Restoration

    Conventional care focuses on lifelong medication adjustments, never addressing barrier repair, microbial reinoculation, or the 5R healing protocol.

    Gut-healing whole foods: leafy greens, fermented vegetables, bone broth
    The Functional Method

    A Natural Functional Approach to Gut Restoration

    1

    Comprehensive Root Cause Investigation

    We run a deep-dive functional gut panel — GI-Map stool DNA, leaky gut markers, breath testing, and food sensitivities — to map your exact microbial roadblocks.

    2

    Personalized Gut Restoration Protocol

    We build a targeted protocol combining therapeutic nutrition, evidence-based nutraceuticals, and antimicrobials to rebalance your microbiome and digestion.

    3

    Barrier Repair & Inflammation Control

    We repair intestinal permeability (leaky gut), calm systemic inflammation, and reinoculate beneficial bacteria to halt immune overactivation.

    4

    Ongoing Monitoring & Optimization

    We track progress with repeat functional labs, symptom mapping, and strategy reviews — adapting your protocol as your microbiome rebalances.

    Advanced Functional Lab Testing

    We Look Where Others Don't

    Microbiome & Dysbiosis
    GI-Map Stool PCRCommensal BalancePathogen ScreenDiversity Index

    Comprehensive DNA stool analysis reveals the exact balance of beneficial and pathogenic microbes driving your digestive breakdown.

    Intestinal Permeability
    ZonulinLPS / EndotoxinSecretory IgACalprotectin

    Leaky gut markers show whether undigested food and toxins are leaking into your bloodstream, triggering systemic inflammation.

    Digestion & Absorption
    Pancreatic ElastaseBile AcidStool pHFat Malabsorption

    Measures whether you actually break down and absorb nutrients — low enzyme or bile output starves every cell in your body.

    Inflammatory Markers
    hsCRPCalprotectinLactoferrinFecal IgA

    Chronic gut inflammation destroys the microbiome and the intestinal lining — these markers quantify the fire inside.

    Food Sensitivities
    IgG Food PanelGluten / ZonulinDairyCross-Reactivity

    Hidden food sensitivities trigger chronic immune reactions that inflame the gut and silently block healing.

    SIBO & Overgrowth
    H2 / CH4 BreathHydrogenMethaneHydrogen Sulfide

    Small intestinal bacterial overgrowth ferments your food into gas, driving bloating, malabsorption, and nutrient deficiency.

    Functional laboratory
    What Most Doctors Miss

    Standard workups rarely run DNA stool analysis, leaky gut markers, or breath testing — leaving dysbiosis, SIBO, and intestinal permeability completely unaddressed.

    94%

    Root cause detection rate in patients previously told labs were "normal"

    The Protocol

    Four Pillars of Gut Restoration

    🌱

    Therapeutic Nutrition

    • Anti-inflammatory, gut-healing diet
    • Blood sugar stabilization
    • Microbiome-feeding prebiotics
    • Elimination of gut-disrupting foods
    💊

    Targeted Supplementation

    • L-glutamine for barrier repair
    • Digestive enzymes & betaine HCl
    • Targeted probiotic strains
    • Antimicrobials for overgrowth
    🧘

    Lifestyle Medicine

    • Vagal tone & nervous system regulation
    • Stress & cortisol management
    • Circadian-aligned eating windows
    • Gut-supportive movement
    🔄

    Detox & Barrier Support

    • Binders for endotoxin clearance
    • Liver & methylation pathway support
    • Inflammation quenching protocols
    • Reinoculation & rebalancing
    Typical Patient Outcomes at 90 Days

    Clinical Improvement Rates

    84%
    Improvement in bloating & digestion
    79%
    Improvement in brain fog & focus
    73%
    Reduction in gut-driven inflammation
    81%
    Improvement in energy & fatigue
    Book My Strategy Call
    Dr. Brandon Mannie and family
    Meet Your Practitioner

    Dr. Brandon Mannie

    Board-Certified Functional Medicine Practitioner

    Dr. Brandon Mannie is a board-certified functional medicine practitioner with over 400 hours of post-graduate training in clinical nutrition and functional medicine. He graduated from Northwestern Health Sciences University in 2004 and has been in private practice ever since.

    Over the past 20+ years, Dr. Mannie has consulted with more than 3,000 patients — people who were told their labs were "normal," yet still felt far from well. His approach goes beyond symptom management: he investigates the root causes driving chronic illness and builds personalized protocols that restore true, lasting health.

    Dr. Mannie operates a fully virtual telehealth practice, serving patients nationwide. His clinical expertise includes type 2 diabetes, insulin resistance, metabolic syndrome, weight loss resistance, and neuropathy.

    "I've seen patients who were dismissed for years finally get real answers and real results. That's why I do this work."
    2004
    Northwestern Graduate
    400+ Hrs
    Post-Grad Training
    3,000+
    Patients Helped
    100%
    Virtual Practice
    Book My Strategy Call
    Patient Outcomes

    Real People. Real Results.

    These are the stories of patients who were told there was nothing more that could be done — and who chose to look deeper.

    Patient Transformation Story
    Patient Transformation
    "I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong."
    — REAL PATIENT, 90-DAY FUNCTIONAL PROTOCOL

    "After 4 years on Metformin and still feeling exhausted, Dr. Mannie found my issue was cellular resistance and gut inflammation. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."

    Margaret T.67, Retired Teacher

    "I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."

    Margaret T.
    67, Retired Teacher
    Metabolic Reset

    "I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."

    Robert K.
    58, Business Owner
    Insulin Resistance

    "As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."

    Sandra M.
    72, Former Nurse
    Type 2 Diabetes

    "The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."

    David L.
    61, Engineer
    Cellular Detox

    "I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."

    Patricia H.
    64, Artist
    Gut Restoration

    "Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."

    Thomas W.
    69, Retired Military
    Functional Protocol

    "I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."

    Jackie R.
    49, Teacher
    Weight Loss Resistance

    "I was told I'd just have to live with the fatigue. Dr. Mannie proved them wrong. Within 90 days on his protocol, my energy is back and I've lost 15 pounds that wouldn't budge before."

    Margaret T.
    67, Retired Teacher
    Metabolic Reset

    "I was told my fasting glucose was 'normal' — meaning they had no idea why I felt so terrible. The functional labs revealed elevated fasting insulin and systemic inflammation. The targeted protocol changed everything."

    Robert K.
    58, Business Owner
    Insulin Resistance

    "As a nurse, I was skeptical of anything outside conventional medicine. But when conventional medicine failed my Type 2 Diabetes for three years, I had nothing to lose. The root cause approach is exactly what I wish I had been taught."

    Sandra M.
    72, Former Nurse
    Type 2 Diabetes

    "The difference between this approach and everything else I tried is that it actually makes sense. They found the cause — chronic gut inflammation and heavy metal toxicity triggering my immune system — and addressed it systematically."

    David L.
    61, Engineer
    Cellular Detox

    "I had given up on ever having energy to play with my grandkids. The functional protocol — particularly the gut healing and targeted nutrient support — gave me my life back."

    Patricia H.
    64, Artist
    Gut Restoration

    "Three specialists and a decade of suffering. One functional consultation changed the trajectory completely. My metabolic dysfunction had a root cause — and now it has a solution."

    Thomas W.
    69, Retired Military
    Functional Protocol

    "I lost 47 pounds with Dr. Mannie's protocol without starving or resorting to injections. I sleep better, my anxiety is down, and I have boundless energy throughout the day."

    Jackie R.
    49, Teacher
    Weight Loss Resistance
    Auto-sliding (Hover to Pause)
    Got Questions?

    Frequently Asked Questions

    Take The First Step Today

    Ready to Discover Why Your Gut Broke Down and Finally Reclaim Your Health?

    Book a complimentary 1-on-1 strategy call with Dr. Brandon Mannie's clinical team. No obligation, no hard sell — just clinical clarity on your path forward.

    Book Your Strategy Call (629) 263-7772
    Avatar
    Hi there! Have a question? Talk with us here.